Botany,  Biotechnology, Chemistry, Computer, Education, Electronics, English Language, Microbiology, Physics, Psychology and Zoology. They provide a wide range of facilities for teaching, learning and research. 

The laboratories of St. Thomas College fulfil the following objectives:

1. Assist in development of organizational, creative and communicative skills among the students.
2. Reinforcing scientific skills of students namely, observing, classifying, measuring, inferring, predicting, collecting, recording & interpreting data, identifying & controlling variables, defining terms operationally, making hypotheses etc.
3. Enhancing the critical thinking skills of the students specifically, synthesizing, evaluating, applying, generating ideas, expressing ideas and solving problems.
4. Understanding the nature of approach of scientists and how they work, existence of a multiplicity of scientific methods, interrelationships between science and technology and among the various disciplines of science.
5. Refine the reasoning skills of students especially, desire to know & understand, questioning of scientific assumptions, search for data & its meaning, demand for verification, respect for logic, consideration of premises, consideration of consequences, respect for earlier findings/studies etc.
6. Promote the qualities of curiosity, perseverance, confidence, open mindedness, risk taking, creativity & courage among the students.
7. Ensure that the contents of theory are substantiated by appropriate charts and models so as to concretize the scientific theories & their application in the minds of the students.